NXF1

Across TCGA cell cohorts, NXF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,380 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NXF1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of DNA repair, and RNA export from nucleus. Each is linked with NXF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both NXF1-to-partner and partner-to-NXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by NXF1-low versus NXF1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF1→partner) and Y-score (partner→NXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Epigenetic regulation of gene expression →	+0.052	+0.877	.002	<.001	3	18
STOMACH	Regulation of DNA repair →	+0.065	+0.722	.001	<.001	3	17
SOFT_TISSUE	RNA export from nucleus →	+0.153	+0.918	<.001	<.001	3	17
STOMACH	Heterochromatin organization →	+0.093	+0.621	<.001	.001	3	17
BONE	Regulation of double-strand break repair →	+0.088	+0.573	<.001	.001	3	17
STOMACH	Heterochromatin formation →	+0.098	+0.739	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,380 associations by consensus.

Epigenetic regulation of gene expression by NXF1 expression — URINARY_TRACT

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