NWD2

Across TCGA patient cohorts, NWD2 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,065 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NWD2-associated proteins across cancer lineages are RELCH_S439, RELCH_T143, and REM2_S27. Each is linked with NWD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NWD2-to-partner and partner-to-NWD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NWD2 versus RELCH_S439 in GBM, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NWD2→partner) and Y-score (partner→NWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RELCH_S439 →	+0.570	+0.506	<.001	.001	3	1
GBM	RELCH_T143 →	+0.346	+0.378	<.001	.001	3	1
GBM	REM2_S27 →	+0.773	+0.460	<.001	<.001	3	1
GBM	RGS7 →	+0.487	+0.368	<.001	<.001	3	1
GBM	RHOT1_S325 →	+0.644	+0.370	<.001	<.001	3	1
GBM	RIF1_S1772 →	-0.714	-0.737	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,065 associations by consensus.

NWD2 vs RELCH_S439 — GBM

Explore this scatter interactively →