NUTM2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NUTM2A mutation is significantly associated with the RNA expression of many other genes, with 112 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUTM2A-associated genes across cancer lineages are RNU6-497P, MSANTD2P1, and RNU7-29P. Each is linked with NUTM2A in more than 1 cancer types. Because this analysis shows association rather than direction, both NUTM2A-to-partner and partner-to-NUTM2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUTM2A→partner) and Y-score (partner→NUTM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-497P →+0.682+4.358<.001.00132
UCECMSANTD2P1 →+0.107+4.903.003<.00132
UCECRNU7-29P →+0.476+4.722<.001.00432
SKCMRN7SL841P →+0.133+5.199<.001.00331
SKCMRPL12P40 →+0.084+4.594<.001.00831
SKCMRNU2-24P →+0.423+4.628<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

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