NUP85

Across TCGA patient cohorts, NUP85 mutation is significantly associated with the RNA expression of many other genes, with 2,992 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP85-associated genes across cancer lineages are RN7SKP103, RNU6-1228P, and MIR6075. Each is linked with NUP85 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUP85-to-partner and partner-to-NUP85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP103 grouped by NUP85-low versus NUP85-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP85→partner) and Y-score (partner→NUP85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP103 →	+0.090	+4.384	<.001	.008	3	3
CESC	RNU6-1228P →	+0.194	+4.559	<.001	.006	3	3
UCEC	MIR6075 →	+0.242	+2.357	.001	<.001	3	2
CESC	PLCH1-AS1 →	+0.113	+4.069	.001	.005	3	2
CESC	RNVU1-23 →	+0.438	+5.254	<.001	<.001	3	2
CESC	MIR6894 →	+0.426	+3.996	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,992 associations by consensus.

RN7SKP103 by NUP85 expression — CESC

Explore this box plot interactively →