Across TCGA patient cohorts, NUP62CL mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP62CL-associated genes across cancer lineages are A-Raf_pS299, FOXO3a_pS318_S321, and GAPDH. Each is linked with NUP62CL in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP62CL-to-partner and partner-to-NUP62CL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP62CL→partner) and Y-score (partner→NUP62CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.169	-3.321	.001	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.130	-3.449	.020	.005	3	1
UCEC	GAPDH →	+0.619	+2.999	.010	.035	3	1
UCEC	INPP4B →	-0.440	-3.700	.002	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.198	-3.169	.009	.018	3	1
UCEC	JNK2 →	+0.189	+2.000	.034	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

NUP62CL survival (RNA) · tumor vs normal (RNA) · all NUP62CL data types