NUP58

Across TCGA patient cohorts, NUP58 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,342 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP58-associated proteins across cancer lineages are CUL4A, WBP4, and HMGB1. Each is linked with NUP58 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUP58-to-partner and partner-to-NUP58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP58 versus CUL4A in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP58→partner) and Y-score (partner→NUP58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CUL4A →	+0.277	+0.364	<.001	<.001	3	6
LSCC	WBP4 →	+0.303	+0.395	<.001	<.001	3	5
GBM	HMGB1 →	+0.448	+0.441	<.001	<.001	3	5
GBM	BLNK →	-0.488	-0.370	.001	.001	3	4
GBM	DEF6_S590 →	-0.776	-0.415	.003	.007	3	4
LSCC	EVL_S246 →	-0.705	-0.519	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,342 associations by consensus.

NUP58 vs CUL4A — GBM

Explore this scatter interactively →