NUP54

Across TCGA patient cohorts, NUP54 protein abundance is significantly associated with the RNA expression of many other genes, with 12,237 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP54-associated genes across cancer lineages are FPR1, C3AR1, and MIR223HG. Each is linked with NUP54 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUP54-to-partner and partner-to-NUP54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP54 versus FPR1 in OV, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP54→partner) and Y-score (partner→NUP54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FPR1 →	-0.942	-0.137	.005	.007	3	6
LSCC	C3AR1 →	-0.938	-0.220	<.001	<.001	3	6
UCEC	MIR223HG →	-0.886	-0.142	.003	.002	2	6
HNSC	SELPLG →	-0.920	-0.137	.002	.003	3	5
LSCC	GIMAP4 →	-1.022	-0.204	<.001	<.001	3	5
GBM	TLR4 →	-0.934	-0.269	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,237 associations by consensus.

NUP54 vs FPR1 — OV

Explore this scatter interactively →