NUP35

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NUP35 protein abundance is significantly associated with the RNA expression of many other genes, with 16,340 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP35-associated genes across cancer lineages are ERMN, NCF4, and TYROBP. Each is linked with NUP35 in more than 6 cancer types. Because this analysis shows association rather than direction, both NUP35-to-partner and partner-to-NUP35 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP35 versus ERMN in GBM, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP35→partner) and Y-score (partner→NUP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMERMN →-1.558-0.189<.001<.00137
GBMNCF4 →-0.793-0.213.002.00236
GBMTYROBP →-0.931-0.207<.001.00336
GBMTLR4 →-0.945-0.250<.001<.00136
GBMCD300C →-0.754-0.215.003<.00136
GBMC3AR1 →-0.957-0.243<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,340 associations by consensus.

NUP35 vs ERMN — GBM

Per-sample scatter of NUP35 vs ERMN in GBM (Pearson r = -0.53).

Explore this scatter interactively →

Exploration