NUP210L

Across TCGA patient cohorts, NUP210L mutation is significantly associated with the RNA expression of many other genes, with 6,802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP210L-associated genes across cancer lineages are SEH1L, CDC7, and PTTG1. Each is linked with NUP210L in more than 4 cancer types. Because this analysis shows association rather than direction, both NUP210L-to-partner and partner-to-NUP210L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEH1L grouped by NUP210L-low versus NUP210L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP210L→partner) and Y-score (partner→NUP210L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEH1L →	+0.337	+1.949	<.001	<.001	3	5
COAD	CDC7 →	+0.674	+3.584	<.001	.002	3	5
UCEC	PTTG1 →	+0.583	+1.378	<.001	<.001	3	4
UCEC	CDT1 →	+0.758	+1.999	<.001	<.001	3	4
LUSC	FAM72B →	+0.425	+2.924	.001	<.001	3	4
UCEC	PRC1 →	+0.698	+1.657	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,802 associations by consensus.

SEH1L by NUP210L expression — UCEC

Explore this box plot interactively →