NUP210L

Across TCGA pan-cancer cohorts, NUP210L RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of NUP210L’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NUP210L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUP210L is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUAD, LUSC, and KICH are the cancer types where NUP210L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUP210L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.427	<.001	8	view →
LUSC	All	All	−0.180	<.001	6	view →
KICH	Female	All	−0.078	<.001	6	view →
CHOL	All	All	+0.082	.004	3	view →
BRCA	Female	All	+0.088	.029	2	view →
STAD	Male	II,III,IV	+0.072	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

NUP210L–LUAD

Open the LUAD breakdown →