NUP210L

Across TCGA patient cohorts, NUP210L mutation is significantly associated with the total protein of many other genes, with 83 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUP210L-associated genes across cancer lineages are eEF2, 4E-BP1, and INPP4B. Each is linked with NUP210L in more than 4 cancer types. Because this analysis shows association rather than direction, both NUP210L-to-partner and partner-to-NUP210L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by NUP210L-low versus NUP210L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP210L→partner) and Y-score (partner→NUP210L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.246	+1.502	.010	.025	3	5
UCEC	4E-BP1 →	+0.313	+3.321	<.001	<.001	3	5
COAD	INPP4B →	-0.523	-3.584	<.001	.002	3	4
COAD	PCNA →	+0.250	+2.708	.012	.003	3	4
COAD	Cyclin-E2 →	+0.216	+3.169	.021	.017	3	4
UCEC	ERK2 →	+0.126	+1.146	.015	.011	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

eEF2 by NUP210L expression — UCEC

Explore this box plot interactively →