NUP210

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NUP210 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NUP210 data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NUP210 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NUP210 expression acts as an unfavorable survival marker.

LUAD and SKCM are the cancer types where NUP210 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianII,III,IV0.1530.682<.00112view →
SKCMDFSMedianIII,IV0.3620.666.0481view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NUP210–LUAD (OS)

Kaplan–Meier survival curve for NUP210 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration