NUP210

Across TCGA pan-cancer cohorts, NUP210 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of NUP210’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where NUP210 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUP210 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BLCA, COAD, and LUAD are the cancer types where NUP210 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUP210 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+1.917	<.001	11	view →
COAD	Female	All	+1.833	<.001	11	view →
LUAD	Male	III,IV	+1.918	<.001	9	view →
LIHC	All	II,III,IV	+1.258	<.001	9	view →
KIRP	All	III,IV	+0.918	<.001	9	view →
STAD	All	II,III,IV	+1.615	<.001	8	view →
THCA	Female	All	−0.681	<.001	8	view →
UCEC	All	III,IV	+3.530	<.001	6	view →
BRCA	All	III,IV	+1.984	<.001	6	view →
HNSC	Male	All	+1.345	<.001	6	view →
LUSC	Male	II,III,IV	+1.001	<.001	5	view →
CHOL	All	All	+1.258	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

NUP210–BLCA

Open the BLCA breakdown →