NUP210

Across TCGA pan-cancer cohorts, NUP210 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NUP210 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NUP210 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NUP210 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, PDAC, and LUAD are the cancer types where NUP210 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.988	0.858	.012	16	view →
PDAC	OS	Median	III,IV	0.359	0.805	.014	12	view →
LUAD	OS	Median	II,III,IV	0.796	0.501	.021	6	view →
CCRCC	OS	Tertile	All	0.722	0.892	.033	4	view →
UCEC	DFS	Median	All	0.841	0.968	.005	4	view →
GBM	OS	Median	All	0.515	0.294	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NUP210–LSCC (DFS)

Open the LSCC breakdown →