NUP210

Across TCGA cell cohorts, NUP210 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUP210-associated genes across cancer lineages are EPC1, ARRB2, and CCDC171. Each is linked with NUP210 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUP210-to-partner and partner-to-NUP210 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPC1 grouped by NUP210-low versus NUP210-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP210→partner) and Y-score (partner→NUP210) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	EPC1 →	+0.400	+2.351	.009	.001	3	2
LARGE_INTESTINE	ARRB2 →	+0.691	+2.000	.004	.009	3	2
LARGE_INTESTINE	CCDC171 →	+0.316	+2.351	.003	.001	3	2
LARGE_INTESTINE	PROP1 →	+0.015	+1.884	<.001	.002	3	2
LARGE_INTESTINE	RNLS →	-1.146	-3.169	.002	.006	3	2
LARGE_INTESTINE	ZNF490 →	+0.340	+2.438	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

EPC1 by NUP210 expression — LARGE_INTESTINE

Explore this box plot interactively →