NUP205

Across TCGA cell cohorts, NUP205 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUP205-associated GO terms across cancer lineages are Mitotic spindle elongation, Replication fork processing, and DNA-templated DNA replication maintenance of fidelity. Each is linked with NUP205 in more than 17 cancer types. Because this analysis shows association rather than direction, both NUP205-to-partner and partner-to-NUP205 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by NUP205-low versus NUP205-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP205→partner) and Y-score (partner→NUP205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Mitotic spindle elongation →	+0.304	+1.039	<.001	<.001	3	18
BONE	Replication fork processing →	+0.116	+0.985	.003	.004	3	18
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.113	+1.082	.004	.002	3	18
KIDNEY	Mitotic spindle midzone assembly →	+0.304	+1.039	<.001	<.001	3	18
BONE	DNA replication initiation →	+0.183	+1.173	.001	<.001	3	18
BONE	DNA replication checkpoint signaling →	+0.197	+1.219	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,136 associations by consensus.

Mitotic spindle elongation by NUP205 expression — KIDNEY

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