NUP188

Across TCGA patient cohorts, NUP188 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,990 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUP188-associated proteins across cancer lineages are PRRC2B, SUPT16H, and NCBP2. Each is linked with NUP188 in more than 6 cancer types. Because this analysis shows association rather than direction, both NUP188-to-partner and partner-to-NUP188 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUP188 versus PRRC2B in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP188→partner) and Y-score (partner→NUP188) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRRC2B →	+0.321	+0.436	<.001	<.001	3	7
GBM	SUPT16H →	+0.318	+0.329	<.001	<.001	3	7
GBM	NCBP2 →	+0.354	+0.522	<.001	<.001	3	7
BRCA	C9orf78 →	+0.325	+0.570	<.001	<.001	3	7
GBM	EHMT1 →	+0.307	+0.434	<.001	<.001	3	7
LSCC	FUBP3 →	+0.235	+0.628	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,990 associations by consensus.

NUP188 vs PRRC2B — LSCC

Explore this scatter interactively →