NUP153

Across TCGA cell cohorts, NUP153 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,346 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUP153-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Negative regulation of nucleobase-containing compound transport, and Regulation of RNA export from nucleus. Each is linked with NUP153 in more than 19 cancer types. Because this analysis shows association rather than direction, both NUP153-to-partner and partner-to-NUP153 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by NUP153-low versus NUP153-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUP153→partner) and Y-score (partner→NUP153) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of RNA export from nucleus →	+0.165	+1.061	<.001	<.001	3	20
BONE	Negative regulation of nucleobase-containing compound transport →	+0.207	+1.178	.002	<.001	3	19
BONE	Regulation of RNA export from nucleus →	+0.135	+0.835	.001	.007	2	20
OVARY	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.126	+0.810	<.001	.002	3	19
OVARY	rRNA 5'-end processing →	+0.126	+0.810	<.001	.002	3	19
BONE	Interstrand cross-link repair →	+0.101	+1.158	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

Negative regulation of RNA export from nucleus by NUP153 expression — PANCREAS

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