NUMBL

Across TCGA patient cohorts, NUMBL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,825 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUMBL-associated proteins across cancer lineages are PCOLCE, VCAN, and NUMBL_S263. Each is linked with NUMBL in more than 5 cancer types. Because this analysis shows association rather than direction, both NUMBL-to-partner and partner-to-NUMBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUMBL versus PCOLCE in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUMBL→partner) and Y-score (partner→NUMBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+0.961	+1.114	<.001	<.001	3	6
OV	VCAN →	+1.278	+1.067	<.001	<.001	3	5
CCRCC	NUMBL_S263 →	+0.731	+0.695	<.001	<.001	3	5
LSCC	UCHL1 →	+1.254	+0.766	<.001	<.001	3	5
CCRCC	VCAN_S2116 →	+1.165	+0.508	<.001	.001	3	5
CCRCC	THBS3 →	+0.930	+0.674	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,825 associations by consensus.

NUMBL vs PCOLCE — OV

Explore this scatter interactively →