NUMBL

Across TCGA patient cohorts, NUMBL protein abundance is significantly associated with the RNA expression of many other genes, with 18,149 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NUMBL-associated genes across cancer lineages are MAP1A, SRPX, and PCOLCE. Each is linked with NUMBL in more than 8 cancer types. Because this analysis shows association rather than direction, both NUMBL-to-partner and partner-to-NUMBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUMBL versus MAP1A in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUMBL→partner) and Y-score (partner→NUMBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAP1A →	+0.862	+0.245	<.001	.001	3	9
CCRCC	SRPX →	+1.147	+0.545	<.001	<.001	3	8
OV	PCOLCE →	+1.105	+0.425	<.001	<.001	3	8
UCEC	SFRP4 →	+2.047	+0.347	<.001	<.001	3	8
OV	AEBP1 →	+1.646	+0.378	<.001	<.001	3	8
OV	ASPN →	+1.627	+0.360	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,149 associations by consensus.

NUMBL vs MAP1A — HNSC

Explore this scatter interactively →