NUMBL

Across TCGA cell cohorts, NUMBL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,041 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUMBL-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Protein depolymerization, and Neuroblast division in subventricular zone. Each is linked with NUMBL in more than 15 cancer types. Because this analysis shows association rather than direction, both NUMBL-to-partner and partner-to-NUMBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by NUMBL-low versus NUMBL-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUMBL→partner) and Y-score (partner→NUMBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.068	+1.492	<.001	<.001	3	16
LUNG_SCLC	Protein depolymerization →	+0.106	+0.997	<.001	<.001	3	16
SOFT_TISSUE	Neuroblast division in subventricular zone →	+0.202	+1.186	<.001	<.001	3	16
BONE	Cytosolic transport →	+0.058	+1.000	<.001	<.001	3	16
BONE	Positive regulation of cell morphogenesis →	+0.081	+1.086	<.001	<.001	3	16
STOMACH	Positive regulation of dendrite morphogenesis →	+0.127	+1.692	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,041 associations by consensus.

Retrograde transport, endosome to Golgi by NUMBL expression — SOFT_TISSUE

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