NUMA1

Across TCGA patient cohorts, NUMA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,584 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUMA1-associated proteins across cancer lineages are HDLBP, FMNL1_S184, and SMC3. Each is linked with NUMA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUMA1-to-partner and partner-to-NUMA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUMA1 versus HDLBP in LSCC, with a Pearson correlation of -0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUMA1→partner) and Y-score (partner→NUMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HDLBP →	-0.346	-0.633	<.001	<.001	3	6
LSCC	FMNL1_S184 →	-0.731	-0.483	.007	.005	3	6
GBM	SMC3 →	+0.322	+0.306	.001	.007	3	5
GBM	BRD3 →	+0.295	+0.322	<.001	<.001	3	5
GBM	CPSF7 →	+0.306	+0.381	<.001	<.001	3	5
BRCA	RING1 →	+0.258	+0.647	.002	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,584 associations by consensus.

NUMA1 vs HDLBP — LSCC

Explore this scatter interactively →