NUFIP2

Across TCGA cell cohorts, NUFIP2 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUFIP2-associated genes across cancer lineages are C14orf180, AVP, and CABP5. Each is linked with NUFIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUFIP2-to-partner and partner-to-NUFIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf180 grouped by NUFIP2-low versus NUFIP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUFIP2→partner) and Y-score (partner→NUFIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C14orf180 →	+0.133	+2.892	<.001	.003	3	2
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	CABP5 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DEFB129 →	+0.043	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	REG3G →	+0.040	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	MROH2B →	+0.085	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

C14orf180 by NUFIP2 expression — LARGE_INTESTINE

Explore this box plot interactively →