NUDT8

Across TCGA cell cohorts, NUDT8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,379 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDT8-associated GO terms across cancer lineages are Butyryl-CoA catabolic process, Propionyl-CoA metabolic process, and Malonyl-CoA catabolic process. Each is linked with NUDT8 in more than 16 cancer types. Because this analysis shows association rather than direction, both NUDT8-to-partner and partner-to-NUDT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Butyryl-CoA catabolic process grouped by NUDT8-low versus NUDT8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT8→partner) and Y-score (partner→NUDT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Butyryl-CoA catabolic process →	+0.971	+1.113	.003	<.001	3	17
OVARY	Propionyl-CoA metabolic process →	+0.151	+1.475	<.001	<.001	3	17
LIVER	Malonyl-CoA catabolic process →	+1.284	+0.850	<.001	<.001	3	16
LIVER	Coenzyme A catabolic process →	+1.132	+0.851	.003	.004	3	15
LUNG_NSCLC_LUSC	Medium-chain fatty-acyl-CoA catabolic process →	+0.130	+1.142	.003	<.001	2	16
UPPER_AERODIGESTIVE_TRACT	Succinyl-CoA catabolic process →	+0.132	+1.551	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,379 associations by consensus.

Butyryl-CoA catabolic process by NUDT8 expression — LIVER

Explore this box plot interactively →