NUDT7

Across TCGA cell cohorts, NUDT7 mutation is significantly associated with the mutation status of many other genes, with 4,036 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUDT7-associated genes across cancer lineages are ECPAS, EPG5, and SLC15A1. Each is linked with NUDT7 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUDT7-to-partner and partner-to-NUDT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ECPAS grouped by NUDT7-low versus NUDT7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT7→partner) and Y-score (partner→NUDT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ECPAS →	+2.754	+4.095	.009	.009	1	4
OVARY	EPG5 →	+4.562	+5.217	<.001	<.001	1	4
LARGE_INTESTINE	SLC15A1 →	+3.137	+3.807	.001	.001	1	3
LARGE_INTESTINE	LAMB1 →	+2.874	+3.632	.002	.002	1	3
LARGE_INTESTINE	JPH4 →	+4.459	+4.459	<.001	<.001	1	3
OVARY	SLC5A4 →	+4.977	+4.415	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,036 associations by consensus.

ECPAS by NUDT7 expression — OVARY

Explore this box plot interactively →