NUDT6

Across TCGA patient cohorts, NUDT6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,116 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT6-associated genes across cancer lineages are GMPR2, EARS2, and ABHD14B. Each is linked with NUDT6 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUDT6-to-partner and partner-to-NUDT6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT6 versus GMPR2 in UCEC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT6→partner) and Y-score (partner→NUDT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMPR2 →	+0.732	+0.340	<.001	.003	3	3
BRCA	EARS2 →	+0.599	+0.517	<.001	<.001	3	3
UCEC	ABHD14B →	+0.656	+0.382	<.001	.001	3	3
UCEC	ACADM →	+0.716	+0.467	.004	<.001	3	3
UCEC	HSDL2 →	+0.889	+0.372	.003	.004	3	3
UCEC	PPA2 →	+0.527	+0.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,116 associations by consensus.

NUDT6 vs GMPR2 — UCEC

Explore this scatter interactively →