NUDT6

Across TCGA cell cohorts, NUDT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,530 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDT6-associated GO terms across cancer lineages are NMDA selective glutamate receptor signaling pathway, Fatty acid oxidation, and Fatty acid catabolic process. Each is linked with NUDT6 in more than 8 cancer types. Because this analysis shows association rather than direction, both NUDT6-to-partner and partner-to-NUDT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NMDA selective glutamate receptor signaling pathway grouped by NUDT6-low versus NUDT6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT6→partner) and Y-score (partner→NUDT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	NMDA selective glutamate receptor signaling pathway →	-0.384	-1.133	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Fatty acid oxidation →	+0.077	+1.117	.002	.003	2	9
BLOOD_Myeloma	Fatty acid catabolic process →	+0.053	+0.768	.001	.005	3	8
URINARY_TRACT	Depurination →	+0.135	+0.609	<.001	.004	2	8
LARGE_INTESTINE	U1 snRNA 3'-end processing →	+0.087	+0.634	<.001	.003	3	7
LARGE_INTESTINE	U5 snRNA 3'-end processing →	+0.087	+0.634	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,530 associations by consensus.

NMDA selective glutamate receptor signaling pathway by NUDT6 expression — URINARY_TRACT

Explore this box plot interactively →