NUDT4B

Across TCGA patient cohorts, NUDT4B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,104 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NUDT4B-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Regulation of autophagosome assembly, and Vesicle tethering involved in exocytosis. Each is linked with NUDT4B in more than 11 cancer types. Because this analysis shows association rather than direction, both NUDT4B-to-partner and partner-to-NUDT4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by NUDT4B-low versus NUDT4B-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT4B→partner) and Y-score (partner→NUDT4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Establishment of mitotic sister chromatid cohesion →	+0.043	+0.043	<.001	<.001	3	12
STAD	Regulation of autophagosome assembly →	+0.033	+0.132	.001	<.001	2	12
STAD	Vesicle tethering involved in exocytosis →	+0.053	+0.147	<.001	<.001	3	11
STAD	Vesicle tethering →	+0.045	+0.146	<.001	<.001	2	12
STAD	Insulin-like growth factor receptor signaling pathway →	+0.050	+0.182	<.001	<.001	3	11
STAD	Negative regulation of protein sumoylation →	+0.057	+0.185	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,104 associations by consensus.

Establishment of mitotic sister chromatid cohesion by NUDT4B expression — KIRP

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