NUDT4B

Across TCGA pan-cancer cohorts, NUDT4B RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated NUDT4B data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NUDT4B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NUDT4B expression acts as an unfavorable survival marker, although some lineages such as STAD and READ show a favorable association.

UCS, THCA, and STAD are the cancer types where NUDT4B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	II,III,IV	0.001	0.616	<.001	90	view →
THCA	OS	Tertile	II,III,IV	0.205	0.844	<.001	39	view →
STAD	OS	Quartile	III,IV	0.569	0.184	<.001	37	view →
COAD	DFS	Tertile	IV	0.237	0.527	.004	36	view →
LUAD	OS	Tertile	II,III,IV	0.478	0.731	<.001	36	view →
READ	DFS	Tertile	III,IV	0.942	0.686	.023	33	view →
SKCM	DFS	Tertile	II,III,IV	0.574	0.712	.005	24	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
PAAD	DFS	Tertile	III,IV	0.275	0.794	.008	15	view →
ESCA	DFS	Median	II,III,IV	0.293	1.000	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

NUDT4B–UCS (OS)

Open the UCS breakdown →