NUDT18

Across TCGA patient cohorts, NUDT18 protein abundance is significantly associated with the RNA expression of many other genes, with 13,190 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUDT18-associated genes across cancer lineages are SPC25, BEND3, and SYPL1P2. Each is linked with NUDT18 in more than 4 cancer types. Because this analysis shows association rather than direction, both NUDT18-to-partner and partner-to-NUDT18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT18 versus SPC25 in GBM, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT18→partner) and Y-score (partner→NUDT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPC25 →	-0.755	-0.320	<.001	<.001	3	5
BRCA	BEND3 →	-0.586	-0.243	<.001	<.001	3	5
LSCC	SYPL1P2 →	-0.650	-0.243	<.001	.001	3	5
LSCC	TMEM97 →	-0.787	-0.182	<.001	<.001	3	5
LUAD	CCT3 →	-0.651	-0.203	<.001	<.001	3	5
GBM	DCPS →	-0.371	-0.313	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,190 associations by consensus.

NUDT18 vs SPC25 — GBM

Explore this scatter interactively →