NUDT18

Across TCGA cell cohorts, NUDT18 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,456 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NUDT18-associated GO terms across cancer lineages are Purine deoxyribonucleoside diphosphate metabolic process, Vacuole fusion, and Late endosome to lysosome transport. Each is linked with NUDT18 in more than 13 cancer types. Because this analysis shows association rather than direction, both NUDT18-to-partner and partner-to-NUDT18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine deoxyribonucleoside diphosphate metabolic process grouped by NUDT18-low versus NUDT18-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT18→partner) and Y-score (partner→NUDT18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Purine deoxyribonucleoside diphosphate metabolic process →	-0.189	-0.887	<.001	<.001	3	14
STOMACH	Vacuole fusion →	+0.117	+1.057	.001	.006	2	11
LARGE_INTESTINE	Late endosome to lysosome transport →	+0.118	+0.888	<.001	<.001	3	9
CNS	Gliogenesis →	+0.070	+1.075	<.001	<.001	3	9
STOMACH	Regulation of pattern recognition receptor signaling pathway →	+0.059	+1.061	.001	.004	2	10
URINARY_TRACT	snoRNA guided rRNA pseudouridine synthesis →	-0.118	-1.125	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,456 associations by consensus.

Purine deoxyribonucleoside diphosphate metabolic process by NUDT18 expression — LUNG_SCLC

Explore this box plot interactively →