NUDT16P1

Across TCGA patient cohorts, NUDT16P1 mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT16P1-associated genes across cancer lineages are LINC02644, RAB28P2, and RNU6-974P. Each is linked with NUDT16P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT16P1-to-partner and partner-to-NUDT16P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02644 grouped by NUDT16P1-low versus NUDT16P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT16P1→partner) and Y-score (partner→NUDT16P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02644 →	+0.241	+3.747	<.001	.003	3	2
UCEC	RAB28P2 →	+0.104	+4.137	<.001	.008	3	2
BRCA	RNU6-974P →	+0.343	+8.471	<.001	.005	3	1
BRCA	MTCYBP2 →	+0.184	+8.471	<.001	.005	3	1
BRCA	DEFB130D →	+0.178	+8.055	<.001	.007	3	1
BRCA	TSPY19P →	+0.089	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

LINC02644 by NUDT16P1 expression — UCEC

Explore this box plot interactively →