Across TCGA pan-cancer cohorts, NUDT16L1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated NUDT16L1 data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher NUDT16L1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NUDT16L1 expression acts as an unfavorable survival marker.
PRAD are the cancer types where NUDT16L1 Mutation most reproducibly stratifies survival.