NUDT16L1

Across TCGA cell cohorts, NUDT16L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,897 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUDT16L1-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, CAMP/PKA signal transduction, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with NUDT16L1 in more than 13 cancer types. Because this analysis shows association rather than direction, both NUDT16L1-to-partner and partner-to-NUDT16L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by NUDT16L1-low versus NUDT16L1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT16L1→partner) and Y-score (partner→NUDT16L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.155	+0.731	<.001	<.001	3	14
BONE	CAMP/PKA signal transduction →	+0.186	+0.612	<.001	<.001	3	13
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.109	+0.808	<.001	<.001	3	12
BONE	Electron transport coupled proton transport →	+0.109	+0.808	<.001	<.001	3	12
BONE	DNA double-strand break processing involved in repair via single-strand annealing →	+0.104	+0.961	<.001	<.001	3	12
BONE	Double-strand break repair via single-strand annealing →	+0.104	+0.961	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,897 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by NUDT16L1 expression — BONE

Explore this box plot interactively →