Across TCGA patient cohorts, NUDT11 mutation is significantly associated with the RNA expression of many other genes, with 3,133 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT11-associated genes across cancer lineages are RNU6-1082P, RNA5SP422, and RNU6-406P. Each is linked with NUDT11 in more than 2 cancer types. Because this analysis shows association rather than direction, both NUDT11-to-partner and partner-to-NUDT11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT11→partner) and Y-score (partner→NUDT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1082P →	+0.397	+5.124	<.001	.008	3	3
UCEC	RNA5SP422 →	+0.613	+1.823	<.001	.001	3	3
BRCA	RNU6-406P →	+1.078	+5.096	<.001	.008	3	2
UCEC	RNA5SP412 →	+0.345	+1.889	.007	.002	3	2
HNSC	DEFB136 →	+0.170	+5.182	.001	.007	3	2
UCEC	RNA5SP410 →	+0.615	+2.161	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,133 associations by consensus.

Exploration

NUDT11 survival (RNA) · tumor vs normal (RNA) · all NUDT11 data types