NUDT1

Across TCGA patient cohorts, NUDT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,248 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUDT1-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with NUDT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both NUDT1-to-partner and partner-to-NUDT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT1 versus RRM2 in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT1→partner) and Y-score (partner→NUDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRM2 →	+0.714	+0.608	<.001	<.001	3	9
BRCA	SMC2 →	+0.826	+0.841	<.001	<.001	3	9
GBM	SMC4 →	+0.729	+0.623	<.001	<.001	3	9
GBM	CDK1 →	+0.721	+0.608	<.001	<.001	3	9
LSCC	RFC2 →	+0.447	+0.743	<.001	<.001	3	8
BRCA	RIF1_S782 →	+1.048	+1.020	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,248 associations by consensus.

NUDT1 vs RRM2 — GBM

Explore this scatter interactively →