NUDC

Across TCGA patient cohorts, NUDC mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDC-associated genes across cancer lineages are G6PD, Ku80, and p27_pT198. Each is linked with NUDC in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDC-to-partner and partner-to-NUDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G6PD grouped by NUDC-low versus NUDC-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDC→partner) and Y-score (partner→NUDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	G6PD →	-0.352	-3.169	.047	.020	3	1
UCEC	Ku80 →	+0.278	+2.817	.032	.036	3	1
UCEC	p27_pT198 →	+0.156	+3.169	.007	.020	2	1
UCEC	PCNA →	+0.329	+3.169	.005	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

G6PD by NUDC expression — UCEC

Explore this box plot interactively →