NUDC

Across TCGA cell cohorts, NUDC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,022 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDC-associated GO terms across cancer lineages are Mitotic spindle elongation, Mitotic spindle midzone assembly, and Nuclear chromosome segregation. Each is linked with NUDC in more than 17 cancer types. Because this analysis shows association rather than direction, both NUDC-to-partner and partner-to-NUDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by NUDC-low versus NUDC-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDC→partner) and Y-score (partner→NUDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.290	+1.055	<.001	.001	3	18
LUNG_NSCLC_LUSC	Mitotic spindle midzone assembly →	+0.290	+1.055	<.001	.001	3	18
BONE	Nuclear chromosome segregation →	+0.134	+0.737	.006	.006	3	18
OESOPHAGUS	Spindle elongation →	+0.279	+0.793	<.001	.001	3	17
BONE	DNA replication initiation →	+0.151	+0.570	<.001	<.001	3	17
BONE	Chromosome segregation →	+0.130	+0.786	.005	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,022 associations by consensus.

Mitotic spindle elongation by NUDC expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →