NUCKS1

Across TCGA patient cohorts, NUCKS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUCKS1-associated proteins across cancer lineages are POGZ, IPO9, and NUCKS1_S181. Each is linked with NUCKS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NUCKS1-to-partner and partner-to-NUCKS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUCKS1 versus POGZ in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUCKS1→partner) and Y-score (partner→NUCKS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POGZ →	+0.330	+0.476	<.001	<.001	3	8
LSCC	IPO9 →	+0.364	+0.655	<.001	<.001	3	8
LUAD	NUCKS1_S181 →	+0.843	+0.684	<.001	<.001	2	8
OV	RCOR3 →	+0.505	+0.387	.001	.003	3	7
LSCC	RPRD2 →	+0.292	+0.618	<.001	<.001	3	7
GBM	CBX5 →	+0.465	+0.433	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,098 associations by consensus.

NUCKS1 vs POGZ — GBM

Explore this scatter interactively →