NUCKS1

Across TCGA cell cohorts, NUCKS1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,194 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NUCKS1-associated genes across cancer lineages are TERF2IP, RCL1, and PUM3. Each is linked with NUCKS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NUCKS1-to-partner and partner-to-NUCKS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUCKS1 versus TERF2IP in BONE, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUCKS1→partner) and Y-score (partner→NUCKS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	TERF2IP →	-0.913	-1.086	.002	<.001	3	7
BREAST	RCL1 →	+1.193	+0.887	<.001	.003	3	7
BREAST	PUM3 →	+1.203	+0.776	<.001	<.001	3	7
BREAST	TFF3 →	-5.004	-0.883	<.001	<.001	3	7
STOMACH	ZNF319 →	-0.713	-0.804	.009	.003	3	6
STOMACH	HAGH →	-0.820	-0.831	.004	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,194 associations by consensus.

NUCKS1 vs TERF2IP — BONE

Explore this scatter interactively →