NUCB1-AS1

Across TCGA pan-cancer cohorts, NUCB1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NUCB1-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher NUCB1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NUCB1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

PAAD, UCS, and CHOL are the cancer types where NUCB1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.639	0.333	.002	49	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
CHOL	DFS	Tertile	III,IV	0.251	0.794	.010	36	view →
KIRP	DFS	Quartile	III,IV	0.508	0.885	.005	27	view →
THYM	DFS	Median	II,III,IV	0.712	0.970	.003	26	view →
COAD	OS	Median	II,III,IV	0.671	0.859	.003	23	view →
SKCM	OS	Median	II,III,IV	0.756	0.920	<.001	22	view →
PRAD	DFS	Tertile	All	0.720	0.887	<.001	22	view →
ESCA	OS	Tertile	All	0.353	0.600	.003	21	view →
LGG	OS	Quartile	All	0.781	0.915	<.001	20	view →
BLCA	OS	Median	All	0.535	0.355	.006	15	view →
HNSC	OS	Median	IV	0.776	0.654	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

NUCB1-AS1–PAAD (OS)

Open the PAAD breakdown →