NUBP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NUBP2 mutation is significantly associated with the RNA expression of many other genes, with 479 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUBP2-associated genes across cancer lineages are RN7SL326P, RPA2P3, and MIR8076. Each is linked with NUBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUBP2-to-partner and partner-to-NUBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL326P grouped by NUBP2-low versus NUBP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUBP2→partner) and Y-score (partner→NUBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL326P →+0.190+5.097<.001.00832
UCECRPA2P3 →+0.183+2.317.002.00632
SKCMMIR8076 →+0.442+5.436<.001.00531
SKCMNBEAP5 →+0.280+5.097<.001.00831
SKCMMIR5688 →+0.738+5.436<.001.00531
UCECPRAMEF13 →+0.036+3.579<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 479 associations by consensus.

RN7SL326P by NUBP2 expression — SKCM

Box plot of RN7SL326P in NUBP2-low vs NUBP2-high samples in SKCM.

Explore this box plot interactively →

Exploration