NTSR2

Across TCGA patient cohorts, NTSR2 mutation is significantly associated with the RNA expression of many other genes, with 470 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTSR2-associated genes across cancer lineages are RNASEH1P1, OR1L3, and SNORD116-18. Each is linked with NTSR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NTSR2-to-partner and partner-to-NTSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH1P1 grouped by NTSR2-low versus NTSR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTSR2→partner) and Y-score (partner→NTSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNASEH1P1 →	+0.256	+4.387	.002	.002	3	3
HNSC	OR1L3 →	+0.057	+4.025	<.001	.004	3	2
HNSC	SNORD116-18 →	+0.240	+4.526	<.001	.007	3	2
HNSC	RN7SKP154 →	+0.215	+4.224	<.001	.003	3	2
COAD	SMSP1 →	+0.128	+3.646	<.001	.009	3	2
UCEC	MIR3661 →	+0.666	+2.286	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 470 associations by consensus.

RNASEH1P1 by NTSR2 expression — COAD

Explore this box plot interactively →