NTSR2

Across TCGA pan-cancer cohorts, NTSR2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NTSR2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NTSR2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NTSR2 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

KIRC, LUSC, and STAD are the cancer types where NTSR2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTSR2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.021	.011	6	view →
LUSC	All	All	+0.079	.004	5	view →
STAD	Female	All	−0.074	.034	2	view →
COAD	All	II,III,IV	+0.034	.012	2	view →
LUAD	Female	All	+0.025	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NTSR2–KIRC

Open the KIRC breakdown →