NTSR2

Across TCGA patient cohorts, NTSR2 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTSR2-associated genes across cancer lineages are Ku80, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with NTSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTSR2-to-partner and partner-to-NTSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by NTSR2-low versus NTSR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTSR2→partner) and Y-score (partner→NTSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.326	+3.183	.012	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.959	+3.169	.003	.020	3	1
UCEC	Cyclin-B1 →	+0.665	+3.169	.031	.020	1	2
UCEC	Di-Ras3 →	-0.168	-3.169	.039	.020	2	1
UCEC	p62 Lck ligand →	+0.446	+3.169	.012	.020	1	1
UCEC	Caspase-8 →	-0.304	-3.169	.027	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Ku80 by NTSR2 expression — UCEC

Explore this box plot interactively →