NTSR2

Across TCGA cell cohorts, NTSR2 mutation is significantly associated with the RNA expression of many other genes, with 265 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NTSR2-associated genes across cancer lineages are LSM10, C4orf47, and ZNF280B. Each is linked with NTSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTSR2-to-partner and partner-to-NTSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM10 grouped by NTSR2-low versus NTSR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTSR2→partner) and Y-score (partner→NTSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LSM10 →	+0.528	+3.451	.007	.002	3	2
LARGE_INTESTINE	C4orf47 →	+0.496	+3.541	<.001	<.001	3	2
LARGE_INTESTINE	ZNF280B →	+0.550	+3.169	.005	.009	3	2
BLOOD_Leukemia	GSTA3 →	+0.009	+3.969	.002	.009	3	1
BLOOD_Leukemia	USP17L3 →	+0.012	+3.922	<.001	.002	3	1
LARGE_INTESTINE	VAPA →	+0.591	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 265 associations by consensus.

LSM10 by NTSR2 expression — LARGE_INTESTINE

Explore this box plot interactively →