NTS

Across TCGA patient cohorts, NTS RNA expression is significantly associated with the protein abundance of many other proteins, with 10,201 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NTS-associated proteins across cancer lineages are ZYX, UBE2L6, and USP25. Each is linked with NTS in more than 2 cancer types. Because this analysis shows association rather than direction, both NTS-to-partner and partner-to-NTS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NTS versus ZYX in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NTS→partner) and Y-score (partner→NTS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZYX →	-0.261	-0.945	.006	.002	3	3
LUAD	UBE2L6 →	-0.471	-1.286	<.001	<.001	3	3
HNSC	USP25 →	-0.247	-2.775	<.001	<.001	3	3
HNSC	RPS6KA4 →	-0.367	-2.013	<.001	.001	3	3
HNSC	RUBCN →	-0.234	-2.241	.003	<.001	3	3
HNSC	SCO2 →	+0.265	+2.278	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,201 associations by consensus.

NTS vs ZYX — GBM

Explore this scatter interactively →