NTPCR

Across TCGA patient cohorts, NTPCR mutation is significantly associated with the RNA expression of many other genes, with 1,417 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTPCR-associated genes across cancer lineages are RNA5SP414, IGHD2-2, and SNORD127. Each is linked with NTPCR in more than 1 cancer types. Because this analysis shows association rather than direction, both NTPCR-to-partner and partner-to-NTPCR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP414 grouped by NTPCR-low versus NTPCR-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTPCR→partner) and Y-score (partner→NTPCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP414 →	+0.378	+2.255	.008	.004	3	2
UCEC	IGHD2-2 →	+1.274	+2.302	.001	<.001	3	2
UCEC	SNORD127 →	+0.433	+1.879	.002	.005	3	2
UCEC	RNA5SP419 →	+0.604	+2.424	<.001	.001	3	2
UCEC	RNA5SP413 →	+0.892	+1.955	<.001	.005	3	2
UCEC	RNA5SP422 →	+0.633	+2.019	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,417 associations by consensus.

RNA5SP414 by NTPCR expression — UCEC

Explore this box plot interactively →