NTN5

Across TCGA patient cohorts, NTN5 mutation is significantly associated with the RNA expression of many other genes, with 1,978 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTN5-associated genes across cancer lineages are TIMM9, DHODH, and FAM126A. Each is linked with NTN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTN5-to-partner and partner-to-NTN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM9 grouped by NTN5-low versus NTN5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN5→partner) and Y-score (partner→NTN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIMM9 →	+0.488	+2.732	.005	.003	3	2
SKCM	DHODH →	+0.493	+3.584	<.001	.002	3	2
SKCM	FAM126A →	+0.720	+3.813	.009	<.001	3	2
SKCM	MRPS36 →	+0.398	+2.719	.005	.003	3	2
SKCM	BTF3 →	+0.468	+3.195	.006	.009	3	2
LUSC	LONRF2P1 →	+0.169	+5.517	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,978 associations by consensus.

TIMM9 by NTN5 expression — SKCM

Explore this box plot interactively →