NTN5

Across TCGA cell cohorts, NTN5 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NTN5-associated genes across cancer lineages are UGT2B28, ADAM7, and SLCO6A1. Each is linked with NTN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTN5-to-partner and partner-to-NTN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B28 grouped by NTN5-low versus NTN5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN5→partner) and Y-score (partner→NTN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UGT2B28 →	+0.989	+4.273	<.001	.006	3	1
LARGE_INTESTINE	ADAM7 →	+0.007	+4.930	<.001	.001	3	1
CNS	SLCO6A1 →	+0.122	+4.315	<.001	.006	3	1
CNS	PADI6 →	+0.006	+4.169	.008	.008	3	1
CNS	OR8B4 →	+0.045	+5.357	<.001	.001	3	1
BLOOD_Leukemia	CBLIF →	+0.104	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

UGT2B28 by NTN5 expression — LARGE_INTESTINE

Explore this box plot interactively →